Small intestine cancer incidence statistics

Cases

New cases of small intestine cancer, 2017-2019, UK

 

Proportion of all cases

New cases of small intestine cancer, 2017-2019, UK

 

Age

Peak rate of small intestine cases, 2017-2019, UK

Trend over time

Change in small intestine cancer incidence rates since the early 1990s, UK

Small intestine cancer is not among the 20 most common cancers in the UK, accounting for less than 1% of all new cancer cases (2017-2019).[1-4]

In females in the UK, small intestine cancer is not among the 20 most common cancers (less than 1% of all new female cancer cases). In males in the UK, it is not among the 20 most common cancers (less than 1% of all new male cancer cases).

45% of small intestine cancer cases in the UK are in females, and 55% are in males.

Small intestine cancer incidence rates (European age-standardised (AS) rate Open a glossary item) for persons are similar to the UK average in all the UK constituent countries.

Small Intestine Cancer (C17), Average Number of New Cases Per Year, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2017-2019

  England Scotland Wales Northern Ireland UK
Female Cases 723 83 42 22 869
Crude Rate 2.6 3.0 2.6 2.3 2.6
AS Rate 2.6 2.9 2.4 2.4 2.6
AS Rate - 95% LCL 2.5 2.5 2.0 1.9 2.5
AS Rate - 95% UCL 2.7 3.2 2.9 3.0 2.7
Male Cases 889 90 50 30 1,059
Crude Rate 3.2 3.4 3.3 3.2 3.2
AS Rate 3.6 3.6 3.3 3.8 3.6
AS Rate - 95% LCL 3.5 3.2 2.8 3.0 3.5
AS Rate - 95% UCL 3.8 4.0 3.9 4.6 3.7
Persons Cases 1,612 172 92 51 1,928
Crude Rate 2.9 3.2 2.9 2.7 2.9
AS Rate 3.1 3.2 2.8 3.1 3.1
AS Rate - 95% LCL 3.0 2.9 2.5 2.6 3.0
AS Rate - 95% UCL 3.2 3.5 3.2 3.6 3.1

95% LCL and 95% UCL are the 95% lower and upper confidence limits around the AS Rate Open a glossary item

References

  1. England data were provided by the National Cancer Registration and Analysis Service (NCRAS), part of the National Disease Registration Service (NDRS) in NHS England, on request through the Office for Data Release, January 2023. Similar data can be found here: https://www.cancerdata.nhs.uk/ 

  2.  Northern Ireland data were provided by the Northern Ireland Cancer Registry (NICR) on request, October 2021. Similar data can be found here:http://www.qub.ac.uk/research-centres/nicr/

  3. Welsh data were published by the Welsh Cancer Intelligence and Surveillance Unit (WCISU), Health Intelligence Division, Public Health Wales https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-reporting-tool-official-statistics/ June 2022. 

  4. Scotland data were provided by the Scottish Cancer Registry, Public Health Scotland (PHS) on request, May 2021. Similar data can be found here: https://publichealthscotland.scot/publications/show-all-releases?id=20468

About this data

Data is for UK, 2017-2019, ICD-10 C17.

Last reviewed:

In the UK in 2017-2019, on average each year around a third of new cases (34%) were in people aged 75 and over.[1-4]

Age-specific incidence rates rise steadily from around age 30-34 and more steeply from age 45-49 and drop in the oldest age groups. The highest rates are in the 85 to 89 age group for females and the 80 to 84 age group for males.

Incidence rates are significantly lower for females than males in a number of (mainly older) age groups. The gap is widest at age 90+, when the age-specific incidence rate is 1.9 times lower for females than males.

Small Intestine Cancer (C17), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, UK, 2017-2019

For small intestine cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

 

References

  1. England data were provided by the National Cancer Registration and Analysis Service (NCRAS), part of the National Disease Registration Service (NDRS) in NHS England, on request through the Office for Data Release, January 2023. Similar data can be found here: https://www.cancerdata.nhs.uk/ 

  2.  Northern Ireland data were provided by the Northern Ireland Cancer Registry (NICR) on request, October 2021. Similar data can be found here:http://www.qub.ac.uk/research-centres/nicr/

  3. Welsh data were published by the Welsh Cancer Intelligence and Surveillance Unit (WCISU), Health Intelligence Division, Public Health Wales https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-reporting-tool-official-statistics/ June 2022. 

  4. Scotland data were provided by the Scottish Cancer Registry, Public Health Scotland (PHS) on request, May 2021. Similar data can be found here: https://publichealthscotland.scot/publications/show-all-releases?id=20468

About this data

Data is for UK, 2017-2019, ICD-10 C17.

Last reviewed:

Small intestine cancer European age-standardised (AS) Open a glossary item incidence rates for females and males combined increased by 176% in the UK between 1993-1995 and 2017-2019.[1-4] The increase was of a similar size in females and males.

For females, small intestine cancer AS incidence rates in the UK increased by 176% between 1993-1995 and 2017-2019. For males, small intestine cancer AS incidence rates in the UK increased by 169% between 1993-1995 and 2017-2019.

Over the last decade in the UK (between 2007-2009 and 2017-2019), small intestine cancer AS incidence rates for females and males combined increased by 46%. In females AS incidence rates increased by 46%, and in males rates increased by 43%.

Small Intestine Cancer (ICD-10 C17), European Age-Standardised Incidence Rates, Persons Population, 1993 to 2019

Small intestine cancer incidence rates have increased overall in all broad age groups in females and males combined in the UK since the early 1990s.[1-4] Rates in 0-24s have increased by 466%, in 25-49s have increased by 170%, in 50-59s have increased by 168%, in 60-69s have increased by 185%, in 70-79s have increased by 179% and in 80+s have increased by 166%.

Small Intestine Cancer (ICD-10 C17), European Age-Standardised Incidence Rates per 100,000 Persons Population, By Age, UK, 1993-2019

 

References

  1. England data were provided by the National Cancer Registration and Analysis Service (NCRAS), part of the National Disease Registration Service (NDRS) in NHS England, on request through the Office for Data Release, January 2023. Similar data can be found here: https://www.cancerdata.nhs.uk/ 

  2.  Northern Ireland data were provided by the Northern Ireland Cancer Registry (NICR) on request, October 2021. Similar data can be found here:http://www.qub.ac.uk/research-centres/nicr/

  3. Welsh data were published by the Welsh Cancer Intelligence and Surveillance Unit (WCISU), Health Intelligence Division, Public Health Wales https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-reporting-tool-official-statistics/ June 2022. 

  4. Scotland data were provided by the Scottish Cancer Registry, Public Health Scotland (PHS) on request, May 2021. Similar data can be found here: https://publichealthscotland.scot/publications/show-all-releases?id=20468

About this data

Data is for UK, 1993-2019, ICD-10 C17.

Last reviewed:

The most common specific location for small intestine cancers in the UK is the duodenum (2016-2018).[1-4] Variation of incidence by anatomical site may reflect the physical size of each site, and differences in risk factor exposure by site, among other factors.

Download this data

Cases and percentages may not sum due to rounding

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, July 2021. Similar data can be found here: https://www.ons.gov.uk
  2. Data were provided by ISD Scotland on request, April 2020. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were published by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales, March 2021. https://phw.nhs.wales/services-and-teams/welsh-cancer-intelligence-and-surveillance-unit-wcisu/cancer-incidence-in-wales-2002-2018/.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/

About this data

Data is for UK, 2016-2018, ICD-10 C17. For some cases the specific location of the cancer is not recorded, this may be due to clinical or data recording factors.

Last reviewed:

The number of new small intestine cancer cases on average each year in the UK is projected to rise from around 2,600 cases in 2023-2025 to around 4,500 cases in 2038-2040.[1]

Small intestine cancer incidence rates are projected to rise by 44% in the UK between 2023-2025 and 2038-2040, to 6 cases per 100,000 people on average each year by 2038-2040.[1] This includes a similar increase for males and females.

For females, small intestine cancer European age standardised (AS) Open a glossary item incidence rates in the UK are projected to rise by 52% between 2023-2025 and 2038-2040, to 5 cases per 100,000 per year by 2038-2040.[1] For males, AS rates are projected to rise by 37% between 2023-2025 and 2038-2040, to 6 cases per 100,000 per year by 2038-2040.[1]

Small intestine cancer (C17), Observed and Projected Age-Standardised Incidence Rates, by Sex, UK, 1993-2040

Download the data table (xlsx)

References

Calculated by the Cancer Intelligence Team at Cancer Research UK, February 2023. Age-period-cohort modelling approach described here, using 2020-based population projections (Office for National Statistics) and observed cancer incidence (1975-2018 for England, Scotland and Wales, 1993-2018 for Northern Ireland).

About this data

Projections are based on incidence data from 1975-2018 (England, Scotland and Wales) and 1993-2018 (Northern Ireland); the above figure presents all UK data from 1993-2018 (observed) and 2019-2040 (projected). Number of new cases and age-standardised rates are presented as annual averages for each 3-year rolling period. ICD-10 codes C18-C20.

Projections are based on observed incidence rates and therefore implicitly include changes in cancer risk factors and diagnosis. Confidence intervals are not calculated for the projected figures. Projections are by their nature uncertain because unexpected events in future could change the trend. It is not sensible to calculate a boundary of uncertainty around these already uncertain point estimates. Changes are described as 'increase' or 'decrease' if there is any difference between the point estimates.

More on projections methodology

Last reviewed:

Small intestine cancer incidence rates (European age-standardised (AS) rates Open a glossary item) in England in females are similar in the most deprived quintile compared with the least, and in males are 22% higher in the most deprived quintile compared with the least (2013-2017).[1]

It is estimated that there are around 65 more cases of small intestine cancer each year in males in England than there would be if every deprivation quintile had the same age-specific crude incidence rates as the least deprived quintile.

Small Intestine Cancer (C17), Estimated Average Number of Excess Cases per Year and European Age-Standardised Incidence Rates per 100,000 Population, by Deprivation Quintile, England, 2013-2017

No data are shown for females as the difference in age-standardised incidence rates between most and least deprived quintiles is not significant for females.

References

  1. Calculated by the Cancer Intelligence Team at Cancer Research UK, April 2020. Based on method reported in National Cancer Intelligence Network Cancer by Deprivation in England Incidence, 1996-2010 Mortality, 1997-2011 . Using cancer incidence data 2013-2017 (Public Health England) and population data 2013-2017 (Office for National Statistics) by Indices of Multiple Deprivation 2015 income domain quintile, cancer type, sex, and five-year age band.

About this data

Data is for England, 2013-2017, ICD-10 C17.

Last reviewed:

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