RadNet – our radiation research network
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RadNet is a network of Cancer Research UK centres of excellence with access to cutting edge facilities working to tackle major challenges in radiobiology and radiation oncology.
The seven funded sites have individual strengths in discovery or clinically aligned research and in particular tumour types and modalities. Together, they’re providing the infrastructure and expertise needed to research how to make radiotherapy more effective while minimising side effects.
We’ve invested over £43m into our network since its launch in 2019, establishing a critical mass of activity, expertise and infrastructure across multiple locations. In 2024 we committed a further £24m to support the network as it continues to build its internationally leading research portfolio to attract further funding for radiation research.
Our network
Each location has its own research priorities that build on local strengths. These represent an ideal opportunity to partner with them in shared areas of interest.
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Birmingham
- Proton, helium and boron neutron capture therapy (BNCT) biology
- DNA damage and replication responses
- Development of preclinical models
- Drug-radiation combinations
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Cambridge
- Biological determinants of resistance to conventional and emerging radiation technologies
- Innovative ways of sensitising cancer to radiation to design more effective radiotherapy for patients
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City of London
- Mechanisms of radiation resistance
- Overcoming radioresistance via radiation combinations
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Glasgow
- Cellular determinants of radiation response
- Metabolism and mitochondrial radiobiology
- Socioeconomic determinants of radiotherapy outcomes
- Cross-cutting: pre-clinical and translational research platforms
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Institute of Cancer Research (ICR) and Royal Marsden Hospital
- Reprogramming cellular responses to radiotherapy
- Promoting a therapeutic tumour microenvironment
- Novel radiation delivery platforms
- Forward and reverse translation
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Leeds
- Personalised and adaptive radiotherapy
- Re-irradiation: from discovery to delivery
- Radiotherapy response and resistance
- Cross-cutting: imaging, AI, computational science, real world data and clinical trials
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Manchester
- Radiation-induced local and systemic immune modulation
- Tumour microenvironment, cancer evolution and therapy resistance
- Inclusive and personalised radiotherapy for complex patients
- Cross-cutting: research inclusivity and proton vs photon radiotherapy across all research schemes