DETERMINE for clinicians

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DETERMINE is a tumour agnostic trial. Patients with any type of cancer can be recruited onto the trial regardless of where it started in the body. We welcome informal enquiries to discuss your patient’s eligibility and next steps.  

The patient must fulfil the eligibility criteria for the trial, as well as any criteria within the specific treatment arm to which they enrol to. Experts from across the UK will need to review the patient's clinical and genomic data. Additional tests will then be required to ensure that it's safe for them to take part. 

Eligibility

•  Any adult patient (aged 18 and over) is eligible to join the trial. Children and teenagers may be suitable for some treatments on the trial. This is dependent on evidence from other clinical trials demonstrating it's safe. 

• The patient must have had a genetic alteration identified within their tumour or circulating tumour DNA. This must be identified prior to joining the trial through the NHS Genomics Medicine Service or an alternative next generation sequencing report.

We welcome informal enquiries to discuss your patient’s eligibility and next steps.

Submit an informal enquiry