Cancer of unknown primary (CUP)

Cancer of unknown primary (CUP) means that cancer spread has been found in your body (secondary cancer), but your doctors can't find where the cancer started (the primary cancer). It is sometimes called unknown primary cancer or unknown primary tumour.

The tests and treatments for cancer of unknown primary in children and young adults might be different to adults. The information in this section is for adults with CUP.

What is cancer of unknown primary?

Cancer of unknown primary (CUP) means that cancer spread (secondary cancer) has been found in your body, but doctors don't know where the cancer started (the primary tumour).

Getting diagnosed with cancer of unknown primary (CUP)

Most people are diagnosed with CUP after they become unwell and go to A&E. Others start by seeing their GP. Find out what to expect when you see a GP and the tests you might have.

Stages and types of cancer of unknown primary (CUP)

There is no staging system for cancer of unknown primary (CUP). Doctors can group CUP by the type of cell the cancer started in.

Treatment for cancer of unknown primary (CUP)

Treatment for CUP depends on a number of things, including where the cancer is and your general health. You might have a targeted cancer drug or chemotherapy. Sometimes you may have surgery or radiotherapy to help control your symptoms.

Survival for cancer of unknown primary (CUP)

Survival for cancer of unknown primary depends on many different things such as the type and stage of cancer. No one can tell you exactly how long you will live.